Inayat Shah, Saman Tauqir, Abdul Waheed Mughal, Muhamamd Shahzad, Tasleem Arif


The leading cause of death is CVD worldwide. Physical activity has been labeled as the single most important modifiable risk factor that alters majority of the other risk factors. However, the existing literature about the effective intensity of exercise to influence other modifiable risk factors is obscure and contradictory. Therefore, this study is aimed to find out the effective exercise intensity beneficial enough to influence the other modifiable risk factors. Methodology:

After ethical approval and written informed consent 20 male overweight and apparently healthy participants, (age = 31 ± 6.1 years) were recruited. Participants attended the lab for 4 days one week apart. On day 1, height, weight,  blood pressure,  heart rate,  waist and hip circumference, and body composition was measured using Tinnita body analyzer was measured. Based on submaximal exercise testing the intensity for 50%, 60% and 70% of the predicted maximum heart rates were calculated. On subsequent visits, blood samples for fasting sugar, fasting lipid and insulin were taken. The participants performed exercise test on the treadmill as per calculated intensity for 30mins. Exercise induced thermogenesis and substrate metabolism was calculated using breath by breath analyzer. Post exercise blood sampling for lipid, blood sugar and insulin were taken immediately after intervention. Results: A dose response relationship of exercise with majority of the parameters was found. Exercise intensity of 60% and above were found to be significantly influencing the other modifiable risk factors including cholesterol (0.04 & <0.001), HDL (0.03), Triglyceride (0.023 & <0.01), insulin (0.12 & 0.05) and blood sugar level (0.02 & 0.001). Conclusion: Exercise intensity need to be in the influential range for affecting the other modifiable risk factors. If well planned even a single bout of exercise can be proved beneficial and add towards prevention of CVDs.


CVDs, Exercise, Modifiable risk factors, Physical activity

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